Islands
in uproar over AIDS vaccine trial
PORT OF SPAIN (IPS)�It was supposed to
be their moment of glory. After years of campaigning, the Trinidad
and Tobago government finally gave the green light for local
researchers to be part of an international campaign against the
deadly HIV virus that causes AIDS.
But instead, the researchers and their
supporters have been taking to the radio, television and other
medium in a bid to assure the public that the HIV vaccine trials
are safe and that participants will not end up contracting the
deadly disease.
The vaccine is being developed through an
alliance involving medical research centers in Brazil, Haiti, and
Trinidad and Tobago with the Institute Pasteur, the Institute
Merieux of France and Canada�s Connaught Laboratories.
The vaccine uses canary pox vectors to
transport HIV genes to the host cells. Volunteers here would be
participating in Phase Two of the trials which tests the efficacy
of the vaccine.
In Trinidad and Tobago official figures show
that 1,200 new cases of AIDS were reported last year and there are
over 17,000 persons living with HIV/AIDS in the country.
But the controversy over the vaccine trial has
come about as a result of a statement Health Minister Dr. Hamza
Rafeeq made in Parliament recently while announcing that cabinet
had agreed for the island to participate in the international
effort.
In his prepared text, Dr. Rafeeq said that
before cabinet had given its approval, it had sought clarification
from a government-appointed committee on a number of specific
issues including whether or not the vaccine would make those who
receive it HIV positive.
According to Dr. Rafeeq, questions were raised
about whether the vaccine is likely to cause the disease AIDS? The
committee, made up of medical, church, trade union and university
lecturers said, "no, highly unlikely."
But when the committee was asked, "Will
the vaccine make those who receive it HIV positive," Dr.
Rafeeq said the response was "yes."
"Immunization with these vaccines will
result in HIV antibody positivity. However, tests are available
and the Medical Research Foundation of Trinidad and Tobago (MRFTT)
has access to these biochemical tests which can differentiate
between vaccine produced positivity and native infected positivity,��
the Health Minister said.
Further, he pointed out that the government
reserves the right "to discontinue the vaccine trials in the
event of any unforeseen circumstances that are highly
disadvantageous or inimical to the health or well being of the
volunteers or the larger society."
Dr. Rafeeq also said that the government was
developing a policy to protect volunteers from discrimination
should they become infected and that the researchers should
provide "the best current available treatment in the world��
for the infected person "for the remainder of his or her
life."
But the researchers at the MRFTT say the
Minister�s statements on the issue were far off the mark.
"It is impossible to become HIV positive
from the vaccine,�� says Professor Courtenay Bartholomew, who
is leading the local research team. "What do they mean by the
answer �highly unlikely?� " he asks."
He insists that the vaccine "is not made
from a live HIV virus�� and that since 1987, over 9,000 people
have been participating in the trial in the United States.
The two-year old Trinidad and Tobago Community
Advisory Board (TTCAB) said it too did not share the view that
volunteers would become infected as a result of the trials.
The TTCAB, an independent group, brings
together a number of organizations including churches, the
Registered Nurses Association, Artists Against AIDS and the Tobago
AIDS Society.
"We have access to all information
available worldwide on the trials and other research," says
Bhuela Duke, its chairman. Ms. Duke added that the establishment
of the TTCAB was one of the criteria for allowing this country to
participate in the trials.
But not everyone is convinced.
David Muhammad of the Nation of Islam, who
hosts a weekly radio show on AIDS, said there is
"overwhelming, irrefutable evidence�� that the vaccine
does cause AIDS in individuals, saying the same vaccine being
tested here had originally been tested in Kenya.
"Why did you send it to Africa to test to
see if it is safe for human beings? It is not the intention of the
Nation of Islam to stop the vaccine trial, but to merely provide
all the information. The people should have the information from
all sides,�� he said on radio.
Callers to other radio and television talks
shows this week were raising the possibility of ��human error��
during the trial resulting in the volunteer becoming HIV-positive,
while others saw it as Black people "who do not have a good
track record with whites�� being exploited once more.
"Every cabinet member who voted yes should
become volunteers,�� said a woman caller, with another saying
that "the Third World countries were being targeted by the
various drug companies." |